Obesity, cause, treatment and complication

Based on research conducted by Johns Hopkins Children’s Investigators found that mothers of children with autism have antibodies that can cause disturbances in the fetus while in the womb. The antibodies can cross the placenta and cause changes that lead to autism. Another study in Sacramento, California by Davis MIND Institute and the Center for Children’s Environmental Health also found that the antibodies bind to the body of pregnant women with fetal brain cells, which likely interfere with brain development that could affect the autism.

Autism itself is a disorder with a major problem in the brain and disorders characterized by social interaction, impaired communication and behavior over and over, and 90% patients with no known cause. Genetic, metabolic, and environmental factors associated with the cause of autism is estimated. This research was initiated from the acquisition of an unusual antibody levels in children suffering from autism and from postmortem brain tissue (dead), which provides an immunity disorders (immune system) in an area of the brain. Antibodies are proteins in the body respond to viruses and bacteria or sometimes in a few cases of autoimmune disorders, the antibodies can attack the body’s own cells.

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Based on research conducted by Johns Hopkins Children’s Investigators found that mothers of children with autism have antibodies that can cause disturbances in the fetus in the womb. The antibodies can cross the placenta and cause changes that lead to autism. Another study in Sacramento, California by Davis MIND Institute and the Center for Children’s Environmental Health also found that the antibodies of pregnant women tied with fetus brain cells, which probably disturbing brain development that could affect the autism.

Autism itself is a disorder with a major problem in the brain and characterized by social interaction disorders, communication disorder and repeated behavior, and 90% patients with unknown cause. Genetic, metabolic, and environmental factors was suspected related to the cause of autism. This research was initiated from obtaining an unusual antibody levels in children suffering autism and from postmortem (dead) brain tissue, which shows an immunity disorders (immune system) in an area of the brain. Antibodies are proteins in the body to respond the viruses and bacteria or sometimes on some cases of autoimmune disorders, the antibodies can attack the body’s own cells.

The majority of children with autism do not have autoimmune disease, so the question that needs to be answered is whether the antibodies are found here are provided by maternal antibodies while in the womb that can interfere with fetal brain directly.

To test their hypothesis (Johns Hopkins), the research team used a technique called immunoblotting (Western blot technology) where the antibody is derived from the blood samples were exposed to adult and fetal brain tissue to confirm whether the antibodies recognize and react with specific brain proteins.

Comparing antibody and brain interactions in the sample of 100 mothers with autistic children and 100 mothers with children without autism. Researchers found a greater reactivity of about 40% of mothers with children with autism. Furthermore, the presence of maternal antibodies associated with a decreased development of the child who is one of the signs of autism.

Although the study found no link between autism with antibodies in the fetal brain, but further research is still needed to confirm whether these antibodies can cross the placenta and cause fetal brain damage.

Facts whereby pregnant women with antibodies can cause fetal brain damage, does not mean that women will always have children with autism disorders. Autism itself is a complex condition caused by interaction between genetic factors, immunity, and environmental factors.