Obesity, cause, treatment and complication

When cholesterol in the blood began to cause blockages in blood vessels, due to plaque deposits of LDL cholesterol, the most horrific impact of stroke is a threat in addition to coronary heart disease risk.

Coronary heart disease primarily caused by a process whereby the formation of atherosclerotic plaque in blood vessels which is a degenerative disorder, although influenced by many factors.

Because the degenerative disorder, then with life expectancy growing, it is clear that the incidence will increase. In addition, he often causes sudden death and attacking the highly productive age, the CHD become an important disease.

Symptoms and Signs
Typical ischemic chest pain (like being pressed with weight and spread to the neck, right arm and back) can be caused by stable angina pectoris (SAP), unstable angina pectoris (UAP) or AMI (acute myocardial infarction). Complaints of chest pain that requires serious attention has the following characteristics:

* Chest pain that feels new (<1 month)
* Changes in the quality of chest pain, such as increased frequency or severity of chest pain, or chest pain that is felt at rest
* Chest pain that does not go away with rest or by sublingual nitrate administration

Other symptoms that may accompany the shortness of breath, feeling of floating and fainting (syncope). If the physical examination can be found in hypertension, heart enlargement and abnormal heart sounds and heart noise.

The most important thing in preventing coronary heart disease is by the lifestyle changes that can control risk factors that can aggravate the disease. Periodic cardiac examination could be performed for patients at risk or not.

However, prevention is better than cure. Prevent the accumulation of fatty plaques of LDL cholesterol is more sensible than treating the existing circumstances.

Low antibody levels within the body can cause a person susceptible to cardiovascular disease (heart and blood vessels), particularly stroke in men. Study published in Academic Journal of Atherosclerosis, directing the research to make immunization for cardiovascular disease.

Atherosclerosis (hardening of the arteries) is an inflammation of the blood vessel so that vessel walls become thickened and less elastic. It can cause blood clots and other heart diseases such as coronary heart disease. Until now it is not certain what causes atherosclerosis, but immune system is believed to have an important role. The researchers believe that levels of bad cholesterol, LDL (low-density lipoprotein) play a role in the development of this disease. The team of researchers from the Karolinska Institute in collaboration with Lund University, finds that there is a natural antibody called anti-PC, which has a target against LDL lipid molecules, play an important role in the development of cardiovascular disease.

Research suggests that individuals who have low levels of anti-PC have an increased risk for cardiovascular disease. Risk was further increased in men with stroke, nearly four times. Risk factors of low anti-PC stand alone and does not depend on other risk factors like high blood pressure, high cholesterol, and smoking.

“Our research to obtain data that anti-PC can be used to improve diagnosis and therapy. We are also developing anti-PC as a vaccine to prevent atherosclerosis and cardiovascular disease, “said Professor Johan Frostegard, chairman of the research.

The study involved 349 people who have a period of 12 years of heart attack or stroke and 693 individuals without symptoms of cardiovascular disease.